Research Manifesto

We are focusing on the design and the fabrication of artificial biomedical devices and the study of natural or hybrid biological devices – all operating in micro- or nano-confined media. There are several dimensions of our Group’s interdisciplinarity:

Bio-nano-info interface. Our research is placed at the interface between biomedical and biological, micro- & nano-, and –increasingly, information engineering. All of these three areas contribute to our research both as tools and enablers, as well as applications and markets.

Interaction of biomolecules and cells with surfaces. Our research focus is the design, fabrication and operation of planar biomedical micro/nano-devices, hence the criticality of the interaction of biomolecules and cells with engineered surfaces. These interactions can be classified as 1D-interactions with flat, or near-flat surfaces; 2D to 3D interactions with micro/nanostructured surfaces, and 4D, dynamic interactions (i.e. 3D+time).

More Moore, No Moore, and Further Moore’s Law. Our research gravitates around, and afar from Moore’s Law, which predicts (or dictates) the steady progress of the fabrication technology towards smaller structures. Apart of research on advanced micro and nanofabrication (“More Moore” research), we are however more interested in the opportunities offered by micro- and nano-fabrication of biomedical micro- and nanodevices (“No Moore” research). Finally, in a number of applications, size is not critical at all, but the complexity is, especially in biological devices, be they natural, artificial or hybrid (“Further Moore” research). [Read more about the dimensions of “Moore space” research]. Without being exclusive, we believe that the best return-on-investment for academic research can be obtained by focusing at the forefront of new, in our case engineering, knowledge. [And it is more fun.] Much of this programmatic focus comes from Claasen’s seminal analysis on technology development [read Claasen’s article here].